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產(chǎn)品名稱：
氟康唑/大扶康/麥尼芬/麥道氟康/Fluconazole
產(chǎn)品型號(hào)： K0040更新時(shí)間： 2017-07-10描述：99%
產(chǎn)品介紹
Description
Biochem/physiol Actions Fluconazole is an antifungal agent. It is highly selective inhibitor of fungal cytochrome P-450 sterol C-14 α-demethyllation. Fluconazole is a potent inhibitor of CYP2C9. Fluconazole interferes with fungal ergosterol synthesis and downregulates the metallothionein gene.
Properties
assay ≥99% （HPLC）
form solid
solubility DMSO: 5 mg/mL
Gene Information human ... CYP1A2（1544）
storage temp. room temp
Safety
Personal Protective Equipment dust mask type N95 （US）, Eyeshields, Gloves
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS XZ4810000
References
reference Richardson, K., et al., Antifungal actvity in vivo. Antimicrob. Agents Chemother. 27, 832, （1985）
Rogers, T.E., and Galgiani, J.N., Antifungal activity in vitro. Antimicrob. Agents Chemother. 30, 418, （1986）
MacMillan, M.L., et al., Infection prophylaxis in bone marrow transplantation patients. Am. J. Med. 112, 369, （2002）
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